| Preterm births have increased by more than 10% over the past decade, with racial and socioeconomic disparities persisting over time, according to a new study analyzing more than five million births. |
| Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers. |
| New mouse model research led by scientists at The Ohio State University Wexner Medical Center, College of Medicine and Imperial College London explored how nerve cells repair themselves, which could lead to new treatments for nerve injuries. |
| Dog lovers can attest to the range of benefits that come with having a canine companion, but improved gut health likely isn't one of them. |
| Multiple surgeries could lead to cognitive decline, a University of Sydney study has found, using data from the United Kingdom's Biobank to analyze half a million patients aged 40 to 69 and followed over 20 years of brain scans, cognitive tests and medical records. |
| A pair of studies examining immune response in C. elegans reveal broad implications for understanding pathogen detection in higher animals and the evolutionary origins of immunity itself. |
| Serotonin is often referred to as the "happiness molecule." It plays a critical role in affecting mood levels and is also a neurotransmitter that sends signals within the brain and the body. |
| New research shows the connection between adverse childhood experiences (ACEs), such as physical or emotional abuse, and an increased risk of people growing up to be abusive against older generations. While generational trauma is known to be passed down from parent to child, the study showed that it can also reverberate upwards from parent to older generations. |
| Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of genetic prion disease are genetic Creutzfeldt-Jakob disease (gCJD), fatal familial insomnia (FFI), and Gerstmann-Sträussler-Scheinker (GSS) syndrome. The most common cause of inherited prion diseases is the E200K mutation of the prion protein (PrP). It is often thought that this mutation causes disease by making PrP more susceptible to misfolding into a pathogenic shape (PrPSc). |
| A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer. |
| Lamotrigine, a drug commonly used to treat epilepsy and certain mood disorders, has been shown to be an excellent treatment option for a rare genetic neuromuscular disease known as non-dystrophic myotonia, in a world-first trial led by University College London researchers. |
| Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell's cytoskeleton. Centrosome dysfunction contributes to diseases like cancer and congenital developmental disorders—for which understanding what regulates centrosome function is key. |
| As Mark Hasegawa-Johnson combed through data from his latest project, he was pleasantly surprised to uncover a recipe for Eggs Florentine. Sifting through hundreds of hours of recorded speech will unearth a treasure or two, he said. |
| Researchers at Fred Hutch Cancer Center identified a substantial increase over the past decade in the proportion of patients with cancer in the U.S. who participate in pharmaceutical industry sponsored clinical trials compared to those conducted with federal government support. |
| Researchers with McMaster University have discovered that the protein mutated in patients with Huntington disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves. |
| Two studies have found that the virus that causes COVID-19 is becoming resistant to two drugs used to treat patients with infections. |
| Firearms are the leading cause of death in children in the United States and are linked to over half of youth suicides. Secure storage of firearms (stored locked, unloaded, and separate from the ammunition) can significantly decrease the rates of child and adolescent firearm-related suicides. |
| Children with disabilities in foster care are extremely vulnerable, facing risks of maltreatment and removal from their homes and greater need for health care services. New research suggests that children with specific disabilities in foster care are less likely to find a permanent home and have a higher risk of mortality while in care compared to those without disabilities. |
| Children who are injured by firearms require significantly more inpatient care, have higher medical complication rates and face a greater risk of death than children with other forms of trauma, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition in Orlando, FL. |
| A resurgence of youth seeking a high from "chroming"—the act of inhaling toxic fumes from household items such as nail polish or permanent markers—could be due to videos featuring the practice on the popular social media platform, TikTok, according to new research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition. |
| The number of children who sought treatment at emergency departments for heat-related illnesses increased by 170% from 2012–2023 at two large children's hospitals, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition in Orlando, FL. |
| The opioid epidemic is a leading cause of morbidity and mortality in the United States, and it is increasingly impacting children and teenagers. Naloxone can reverse the effects of opioid overdose and is being used in hospitals and by emergency responders outside the hospital to save the lives of young people poisoned by opioids. |
| Low levels of Vitamin D can impact the healing of fractures in children, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition at the Orange County Convention Center from Sept. 27-Oct. 1. |
| A study found fewer than one in four Colorado residents living with children at home recognized suicide as the leading cause of firearm death and less than half thought suicide can be prevented, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition. |
| Water-absorbing beads have become increasingly hazardous to children over the past 10 years, as children who swallow the beads can experience life-threatening problems such as bowel obstruction. |
| One in three adolescents who have visited a pediatric emergency department report difficulties in accessing menstruation products, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition at the Orange County Convention Center from Sept. 27–Oct. 1. |
| Unintentional injuries like falls, drownings and poisonings are the leading cause of death in patients ages 1–4, and a significant portion of these deaths are linked to unintentional ingestion—such as swallowing a drug or poison. New research shows racial and socioeconomic disparities exist in the emergency management of unintentional ingestions in children. |
| Infants who were exclusively fed breast milk during their hospitalization at birth were 22% less likely to develop asthma in early childhood, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition in Orlando. |
| The risk of being born with a major heart defect is 36% higher in babies who were conceived after assisted reproductive technology, such as in vitro fertilization (IVF), according to results of a very large study published in the European Heart Journal. |
| Australia has seen a rapid rise in mpox cases in the past three months, with one health expert concerned that low vaccination rates could be driving a spike outside cities. |
| Children born in 2020 to 2021 had lower coverage with nearly all childhood vaccines recommended by age 24 months than those born in 2018 and 2019, according to research published in the Sep. 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. |
| Patients with primary thyroid cancer who receive radioactive iodine therapy have an elevated risk for melanoma and other nonkeratinocyte skin cancers when limiting the cancer site to the head and neck, according to a study published online Sept. 19 in JAMA Network Open. |
| Non-Hispanic Black patients in the United States appear to have persistent disparities in terms of hematopoietic cell transplantation (HCT) for various hematologic cancers, according to a study published online Sept. 18 in JAMA Network Open. |
| For 12 years, Paul Stroud's done everything he can to combat the effects of Parkinson's disease. He had a pair of stimulators implanted deep in his brain. He takes the standard medications to treat symptoms. He even briefly tried out tai chi. |
| The first new type of medication in decades to help fight against schizophrenia was approved on Thursday by the U.S. Food and. Drug Administration. |
| A19-year study at the University of Virginia is revealing what may lead some young adults to suffer from debilitating depression and anxiety. |
| In 2022, more than 100,000 people died from opioid overdoses in the U.S., according to the National Center for Health Statistics. Roughly three quarters of these deaths involved fentanyl, a highly potent synthetic opioid. |
| A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert. |
| Sleep deprivation typically results in longer and deeper sleep, thereby maintaining overall sleep quantity and quality through homeostatic regulation. However, the specific mechanisms by which the brain monitors and controls sleep homeostasis remain unclear. |
| Results from a new University of Kentucky Markey Cancer Center study show that molecular tumor boards can play an important role in identifying potential inherited cancer risks, leading to better patient care. |
| Teen vaping has surged to alarming levels, making e-cigarettes the most popular nicotine product among U.S. adolescents. According to the Center for Disease Control and Prevention, 4.6% of middle school and 10% of high school students, or 2.1 million students, used e-cigarettes in 2023. |
| A new intervention which keeps lungs regularly expanding when using a heart-lung machine during heart valve surgery might protect lung function and exercise capacity in adult patients after the operation, a University of Bristol-led clinical trial has found. |
| After a hearty lunch at work, you and your co-workers go into a meeting. First one colleague starts to yawn, then a second and finally it's your turn. Many biological explanations have been put forward for this, but what is the scientific consensus? |
| Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal. |
| Exposure to vape and e-cigarette residue on surfaces while pregnant could put unborn babies at risk of immune system damage, new research suggests. |
| There is unexpectedly large variation in height growth in girls after their first period. Every second girl grows either more or less in length than the 6–8 centimeters that is considered standard. This has been shown in a study conducted at the University of Gothenburg. |
| Houston Methodist researchers have developed an advanced mathematical model that predicts how novel treatment combinations could significantly extend progression-free survival for patients with non-small-cell lung cancer (NSCLC), the most common type of lung cancer. |
| In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption on the lungs. They have found that nearly every cell in the body is keeping track of time. |
| New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in partnership with Sichuan University, Chengdu, has found that people that show traits and behaviors that differ from gender stereotypes may be at greater risk of a range of common mental health difficulties, including anxiety, depression and low self-esteem. |
| Obtaining accurate clinical measurements is essential for diagnosing and treating a wide range of health conditions. Regrettably, the impact of skin type and pigmentation is not equally considered in the design and calibration of non-invasive oxygen-monitoring medical technology. |
| A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in specific transfer RNA (tRNA) levels, disrupting protein synthesis in the brain and impairing synaptic structure and function. |
| Currently, kidney transplantation is the most effective treatment to ensure survival and improve the quality of life of patients with end-stage chronic kidney disease, and it is widely practiced in health care systems. However, the monitoring of transplant patients and markers of tolerance to the transplanted organ remain limited. |
| For infants and young children hospitalized with respiratory syncytial virus (RSV) infection, ziresovir reduces signs and symptoms of bronchiolitis, according to a study published in the Sept. 26 issue of the New England Journal of Medicine. |
| For infants born prematurely, survival increases considerably for those born at 25 versus 22 gestational weeks, according to a study published online Sept. 26 in Pediatrics. |
| An in-home, voice-activated cognitive behavioral therapy (CBT) program improves insomnia symptoms among breast cancer survivors, according to a study published online Sept. 24 in JAMA Network Open. |
| Omitting biopsy in patients with negative magnetic resonance imaging (MRI) results is associated with a significantly reduced relative risk for detecting clinically insignificant prostate cancer, according to a study published in the New England Journal of Medicine. |
| Children born to greater socioeconomic backgrounds are significantly more likely to be prescribed opioids, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition at the Orange County Convention Center from Sept. 27–Oct. 1. |
| The impacts of the ongoing opioid crisis are trickling down to young children, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition at the Orange County Convention Center from Sept. 27–Oct. 1. |
| Some babies are born with abnormalities involving the structure of the heart, known as congenital heart disease (CHD). While many studies have shown that more babies with congenital heart disease are surviving past their first birthday as deaths from CHD have significantly decreased in the United States, a research abstract found that race impacts these survival rates. |
| About 7% of more than 1,000 teens who disclosed sexual abuse at a California hospital reported that social media was used to facilitate the assault, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition. |
| Black and LatinX teenagers enrolled in an eight-week racial justice activism program reported fewer symptoms of depression and anxiety, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition in Orlando, FL. |
| The only firearm restrictions found to be effective in reducing mass shootings involving children were laws banning the sale of firearms equipped with a large-capacity magazines, according to a new analysis presented during the American Academy of Pediatrics 2024 National Conference and Exhibition. |
| Tucked away behind unassuming double doors on the fifth floor of Rush University Medical Center sits a new, very different type of medical unit. |
| Republican vice presidential nominee JD Vance's plan to rework President Barack Obama's signature health care law is vague on details, but many conservative health care experts say it would take the Republican Party back to a place it doesn't want to go. |
| An estimated one-third of patients with major depressive disorder have treatment-resistant depression (TRD), characterized by an inadequate response to two or more oral antidepressants (OADs). |
| World leaders meeting in New York have backed a new set of goals and pledged to find US$100 million in funding to address the problem of drug-resistant bacteria, a global crisis that is all the more acute in the poorest countries. |