 | In laboratory tests, exterior duct tape reduced water leakage through household doors by 97%–98%, compared with a maximum reduction of 70% for sandbags with plastic sheeting. Tape offers temporary protection at door gaps but cannot prevent entry through other routes or replace property-specific flood protection. |
| |
 | Quantum relative entropy at spacetime horizons is related to energy flux across them. Combining this relation with the horizon entropy–area law yields semiclassical Einstein equations, linking quantum information to spacetime curvature without establishing a complete theory of quantum gravity. |
| |
 | Proteomic analysis of ovaries from 28 postmenopausal women aged 50–75 showed age-related increases in inflammation and tissue remodeling. Some cancer-associated proteins increased despite normal, cancer-free tissue. Postmenopausal ovaries remain biologically active, but whether these changes benefit or harm health is unknown. |
| |
 | Pentadecanoic acid produced by Bacteroides uniformis reduced arterial plaque by about half in male mice prone to atherosclerosis. It inhibited HMG-CoA reductase, lowering cholesterol synthesis and increasing liver LDL receptor-mediated clearance. Cardiovascular benefits in humans remain unproven. |
| |
 | Alcohol exposure activated microglia to degrade the brain’s extracellular matrix, reducing neuronal activity and damaging connections and neurons. Deleting microglial MyD88 prevented this damage and reduced sedation despite unchanged blood alcohol levels. Similar matrix disruption occurred in frontal cortex tissue from people with alcohol use disorder. |
| |
 | Grazing two sheep per hectare in solar arrays increased beneficial insect abundance by 38% versus mowing, largely through more honey bees. Eight sheep per hectare maximized vegetation control but reduced honey bee abundance by 45%. A spreadsheet model supports flock purchasing and sales decisions to improve solar grazing profitability. |
| |
 | A proposed framework models consciousness as a balance between coherent neural integration and dissipative processing, using a superconductivity analogy. It identifies SU(3) symmetry as a candidate structure to test in EEG or MEG during meditation and cessation. Shared neural–cosmic symmetry and brain superconductivity remain unestablished. |
| |
 | Among 157,616 pet cats tested in the U.S. and Canada, 6.3% were positive for Giardia duodenalis. Of positive cats, 18.5% carried assemblages A or B, which can infect humans. Detection was highest in kittens, supporting fecal screening to identify potentially zoonotic infections. |
| |
 | Mice receiving gut microbes from people with schizophrenia showed reduced maze alternation and social preference, alongside intestinal inflammation and altered prefrontal microglia. Small donor samples limit generalizability; the results do not establish causal links between immune and behavioral changes or show that gut microbes cause schizophrenia in humans. |
| |
 | In an 80-week randomized trial of 1,152 adults with obesity and type 2 diabetes, weekly retatrutide 12 mg reduced weight by 18.8%, versus 5.1% with placebo. HbA1c fell by 1.4–1.5 percentage points across doses, versus 0.45 with placebo. Gastrointestinal adverse events were common; adverse events led 8–12% to discontinue higher doses, versus 5% with placebo. |
| |
 | In rats with chemically induced chronic colitis, hippocampal inflammation occurred in both sexes, while neuronal damage was greater in males. Creatine given before and during colitis restored hippocampal energy stores and prevented inflammation and male neuronal dysfunction. Effects on memory, mood and human disease remain untested. |
| |
 | Dianjunus rex, discovered in Yunnan, China, produces fruiting bodies up to 50 cm tall and 2.2 kg, the largest known in Ascomycota. Genetic and morphological analyses place it in the new family Dianjunaceae within Xylariales, with molecular dating estimating its lineage originated about 65 million years ago. |
| |
 | Single-cell analysis of 62 pancreatic ductal adenocarcinomas linked clonal genetic diversity to subtype switching, treatment resistance and metastasis. Blocking MYC shifted aggressive basal cells toward a less aggressive classical state and increased their exposure to immune cells. |
| |
 | In a one-month study of 19 owners and 29 cats, greater daily proximity was associated with more positive owner moods. Higher feline urinary oxytocin was linked to lower owner cortisol and fewer negative feelings. These associations do not establish causation. |
| |
 | Losartan increased brown fat activity in cultured cells and energy expenditure in mice without changing body weight. Among over 100,000 patients, brown fat was associated with better cardiometabolic measures and less anxiety and depression. Losartan’s metabolic effects involved a pathway distinct from blood-pressure lowering; human efficacy remains unproven. |
| |
 | Orion’s Artemis II heat shield and backshell performed within engineering predictions during reentry, protecting the crew and onboard systems. A shorter reentry downrange distance reduced heat shield cracking and char loss tenfold relative to Artemis I, with nine char-loss sites versus 103. |
| |
 | Human-vision modeling of white dwarf spectra predicts green, pink, purple, yellow and cyan appearances due to absorption in dense atmospheres. WD J1330+6435 is predicted to appear green because sodium absorbs orange light. Five of 151 nearby white dwarfs had unusual colors; the rest had a median color temperature of about 6,800 K, perceived as white. |
| |
 | Three peptides from Hypsizygus marmoreus enhanced saltiness in NaCl solutions without adding sodium. ASHGEGF increased electronic-tongue saltiness intensity by 70.59% at 3 mg/mL NaCl, and sensory testing showed saltiness lasting up to 105 seconds. Effectiveness and stability in low-sodium foods remain untested. |
| |
 | Groundwater depletion in the Colorado River Basin accelerated after 2019. During the 2020–2022 drought, the Upper Basin lost about 17.4 trillion liters, nearly twice the Lower Basin’s 9.5 trillion liters, reversing the historical pattern. These losses underscore the need to manage groundwater and surface water together. |
| |
 | A proposed superfluid helium-4 gyrometer would measure Earth's frame-dragging through phase shifts across a Josephson junction. Thermal-noise calculations indicate that operation near 10 mK could match existing measurement sensitivities, but experimental realization requires junctions that function at m |
Aucun commentaire:
Enregistrer un commentaire